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Fort Myers Sanibel Car Trips

Getting to and around the Fort Myers Sanibel area by car is easy, with good interstate access and easy-to-navigate local roads.
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Sanibel Causeway toll bridge

Lee County lies on the southwest coast of Florida and is easily reached via major interstate highways.

Interstate Travel

Interstate 10 runs east-west from California to Jacksonville, FL, and Interstate 95 extends from the northeastern U.S. to south Florida. Travelers using I-95 can take Interstate 4 west to connect with southbound Interstate 75. North-south I-75 connects directly to I-10 and is the major highway that traverses Lee County, the home of The Beaches of Fort Myers & Sanibel. I-75 begins in south Florida and ends in the Midwestern U.S.

In-Town Driving

In addition to Interstate 75, major roads that convey motorists in Lee County include U.S. 41, which runs north-south and parallel to the interstate; McGregor Boulevard, which extends from downtown Fort Myers and links with roads leading to Sanibel and Captiva islands and Fort Myers Beach; and State Road 78, which connects the mainland with Pine Island, crossing Cape Coral as it extends south and west.

Tolls

Cape Coral Parkway and Midpoint Memorial bridges have a $1 fee going both ways. The bridge that takes U.S. 41 across the Caloosahatchee River is free. The Sanibel Causeway toll is $6, and is charged only for going to Sanibel Island.

Driving Times and Distances

Distances to Lee County from Cities in Florida

City Miles/Kilometers Drive Time

Daytona Beach 251 miles/403.9 km 4.25 hours
Jacksonville 335 miles/539.1 km 5.25 hours
Miami 158 miles/254.3 km 2.5 hours
Orlando 196 miles/315.4 km 3.5 hours
Tampa 126 miles/202.8 km 2.5 hours

Distances to Lee County from Cities outside Florida

City Miles/Kilometers Drive Time

Boston 1,478 miles/2,379 km 23.5 hours
Chicago 1,290 miles/2,076 km 20 hours
Cincinnati 1,043 miles/1,679 km 16 hours
Cleveland 1,215 miles/1,955 km 18.75 hours
Detroit 1,298 miles/2,089 km 20 hours
Indianapolis 1,109 miles/1,785 km 17 hours
Milwaukee 1,389 miles/2,235 km 21.75 hours
Minneapolis/St. Paul 1,704 miles/2,742 km 26.25 hours
New York 1,264 miles/2,034 km 19.75 hours
Philadelphia 1,174 miles/1,889 km 18.5 hours
St. Louis 1,129 miles/1,817 km 17.25 hours
Washington, D.C. 1,029 miles/1,656 km 15.75 hours

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